Train connections from Lyon and Paris are excellent. The TGV fast train gets you there in about three hours. Typical gateway cities include Aix-en-Provence, Avignon, and Valence. From these cities, one can easily explore the beautiful region. On Saturdays in the summer season, a Eurostar service operates to Avignon direct from London see the Eurostar website for more information (http://www.eurostar.com).